2770. Intrapulmonary Vaccination with an M Protein-Deficient Respiratory Syncytial Virus (RSV) Vaccine Protects Infant Baboons Against an RSV Challenge

BACKGROUND: RSV infection is a major cause of lung disease in infants, yet there is no licensed vaccine. We are developing a live RSV vaccine with a deletion of the M protein (“Mnull RSV”). The RSV M protein is responsible for assembling newly synthesized RSV proteins into intact virus. Mnull RSV in...

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Publicat a:Open Forum Infect Dis
Autors principals: Welliver, Robert C, Oomens, Antonius, Preno, Alisha, Papin, James, Ivanov, Vadim, Staats, Rachel, Norris, Abby, Reuter, Nicole, Piedra, Pedro
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6809773/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.2447
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