1385. Mechanism-Based, In Vitro Inhibition of Mycobacterium abscessus: Assessing β-Lactam Therapy

BACKGROUND: M. abscessus (Mab) is an emerging pathogen, a highly drug-resistant rapidly-growing nontuberculous mycobacteria. Mab L, D transpeptidases (Ldt(Mab 1–5)), D,D carboxypeptidase and Bla(Mab) β-lactamase are important targets. Herein, we tested the susceptibility of ceftaroline (TAR) and imi...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Dousa, Khalid M, Kurz, Sebastian G, Bethel, Christopher R, Barnes, Melissa D, Taracilla, Magdalena A, Selvaraju, Suresh, Jacobs, Michael R, Kreiswirth, Barry, Kasperbauer, Shannon H, Daley, Charles L, Bonomo, Robert A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6809419/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.1249
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