1953. VE303, a Rationally Designed Bacterial Consortium for Prevention of Recurrent Clostridioides difficile (C. Difficile) infection (rCDI), Stably Restores the Gut Microbiota After Vancomycin (vanco)-Induced Dysbiosis in Adult Healthy Volunteers (HV)

BACKGROUND: Gut microbiota alterations and resulting changes in metabolites involved in colonization resistance and host responses, including bile acids (BA) and short-chain fatty acids (SCFA), are hallmarks of C. difficile infection. Reduction in rCDI was shown with fecal microbiota transplants (FM...

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Библиографические подробности
Опубликовано в: :Open Forum Infect Dis
Главные авторы: Bobilev, Dmitri, Bhattarai, Shakti, Menon, Rajita, Klein, Brian, Reddy, Shilpa, Olle, Bernat, Roberts, Bruce, Bucci, Vanni, Norman, Jason
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2019
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Abstracts
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6809015/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz359.130
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