1598. Antimicrobial Activity of the Novel β-Lactam Enhancer Combination Cefepime–Zidebactam (WCK-5222) Tested Against Gram-Negative Bacteria Isolated in United States Medical Centers from Patients with Bloodstream Infections

BACKGROUND: Zidebactam (ZID) is a β-lactam enhancer antibiotic with a dual mechanism of action: high binding affinity to gram-negative PBP2 and β-lactamase (BL) inhibition. We evaluated the activity of cefepime (FEP) combined with ZID against contemporary clinical isolates of gram-negative bacilli (...

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Vydáno v:Open Forum Infect Dis
Hlavní autoři: Castanheira, Mariana, Huband, Michael D, Flamm, Robert K, Sader, Helio S
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6809001/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.1462
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