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971. The Role of Inflammation and Innate Effectors in Passive Immunization for Acinetobacter baumannii Infections

BACKGROUND: We have previously demonstrated that A. baumannii virulence is driven by avoidance of innate effector clearance, resulting in LPS-TLR4 triggering of excess inflammation in the host. We also raised a monoclonal antibody (MAb) that improved survival of mice lethally infected with A. bauman...

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Bibliografiske detaljer
Udgivet i:Open Forum Infect Dis
Main Authors: Nielsen, Travis B, Yan, Jun, Luna, Brian M, Talyansky, Yuli, Bonomo, Robert A, Spellberg, Brad
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6808996/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz359.073
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