1337. Development, Maintenance, and Application of Opsonophagocytic Assays to Measure Functional Antibody Responses to Support a 20 Valent Pneumococcal Conjugate Vaccine

BACKGROUND: Opsonophagocytic assays (OPAs) are an important tool for assessing vaccine-induced functional antibody responses. OPAs are complex assays composed of many biological components (eg serum, complement sources, bacteria, and human phagocytes) which contribute to assay variability and may re...

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Опубликовано в: :Open Forum Infect Dis
Главные авторы: Scully, Ingrid L, Cutler, Mark W, Gangolli, Seema, Belanger, Todd, Cooper, David, Jones, Thomas, McKeen, Andrew, Tan, Charles, Watson, Wendy, Anderson, Annaliesa S, Jansen, Kathrin U, Pride, Michael W
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2019
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Abstracts
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6808972/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.1201
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