2888. STAT4 Mutation in Three Generations with Disseminated Coccidioidomycosis (DCM) also Exhibits Increased Susceptibility to Coccidioidal Infection in Transfected Mice

BACKGROUND: Reported coccidioidomycosis has increased with case rates of 198/100,000 in Arizona (2012). In California alone, 2000–2011 hospitalizations were $2.2B. Dissemination occurs in 8% of reports with significant morbidity and occasional deaths. DCM was found in 3 generations: grandmother (ski...

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Publié dans:Open Forum Infect Dis
Auteurs principaux: Powell, Daniel A, Shubitz, Lisa F, Hsu, Amy, Davis, Joie, Holland, Steven M, Berghout, Joanne, Lussier, Yves A, Frelinger, Jeffrey A, Galgiani, John N
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6808849/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz359.166
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