91. Differential Impact of Cytomegalovirus (CMV) Donor (D) Serostatus on Rates and Kinetics of CMV Viremia among CMV Seropositive Recipients (R+) of Ex vivo T-cell Depleted (TCD) and Unmodified (CONV) Hematopoietic Cell Transplants (HCT)

BACKGROUND: In unmodified (CONV) HCT, CMV donor seropositivity (D+) conveys partial protection against CMV disease mediated by the transfer of donor CMV T-cell immunity through the allograft. Ex vivo T-cell depletion by CD34 selection affords a stringent depletion of donor T cells, thus transfer of...

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Vydáno v:Open Forum Infect Dis
Hlavní autoři: Stern, Anat, Su, Yiqi, Fang, Jiaqi, Perales, Miguel, Maloy, Molly, Giralt, Sergio, Papanicolaou, Genovefa
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6808764/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz359.015
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