Identification of distinctive interferon gene signatures in different types of myositis

OBJECTIVE: Activation of the type 1 interferon (IFN1) pathway is a prominent feature of dermatomyositis (DM) muscle and may play a role in the pathogenesis of this disease. However, the relevance of the IFN1 pathway in patients with other types of myositis such as the antisynthetase syndrome (AS), i...

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Veröffentlicht in:Neurology
Hauptverfasser: Pinal-Fernandez, Iago, Casal-Dominguez, Maria, Derfoul, Assia, Pak, Katherine, Plotz, Paul, Miller, Frederick W., Milisenda, Jose C., Grau-Junyent, Josep M., Selva-O'Callaghan, Albert, Paik, Julie, Albayda, Jemima, Christopher-Stine, Lisa, Lloyd, Thomas E., Corse, Andrea M., Mammen, Andrew L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6808530/
https://ncbi.nlm.nih.gov/pubmed/31434690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000008128
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