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E2 protein is the major determinant of specificity at the human papillomavirus origin of replication

The replication of human papillomavirus (HPV) genomes requires E1 and E2 proteins as the viral trans-factors and the replication origin, located in the URR, as a cis-element. The minimal requirements for an HPV replication origin vary among different virus types but always include one or more bindin...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Laaneväli, Airiin, Ustav, Mart, Ustav, Ene, Piirsoo, Marko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6808437/
https://ncbi.nlm.nih.gov/pubmed/31644607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224334
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