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Robotic inhibition assay for determination of HMG‐CoA reductase inhibitors in human plasma
The cholesterol‐lowering drug simvastatin (SIMV, Zocor(®)) reduced heart attacks by 42% in patients who had high cholesterol levels and suffered from heart disease. Upon oral administration, SIMV is quickly hydrolyzed to its β‐hydroxyacid and other acid metabolites, which are potent inhibitors of 3‐...
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| Veröffentlicht in: | J Clin Lab Anal |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Wiley Subscription Services, Inc., A Wiley Company
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6807993/ https://ncbi.nlm.nih.gov/pubmed/12357448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.10046 |
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