Molecular Detection of Trisomy 21 by Bicolor Competitive Fluorescent PCR

OBJECTIVE: To develop a reliable and specific method for rapid prenatal diagnosis of Trisomy 21 (Down syndrome). METHODS: We established a dual color competitive fluorescent Polymerase Chain Reaction (PCR) to measure the gene dosage of Down syndrome critical region (DSCR), a single copy sequence in...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Wang, Yan, Zhang, Xiaofei, ling, Bo, He, Changxiao, Xia, Qingjie, Chen, Feng, Miyamori, Isamu, Yang, Zhao, Fan, Chunyuan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6807619/
https://ncbi.nlm.nih.gov/pubmed/23686780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.21593
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