Expression of Urokinase‐Type Plasminogen Activator (uPA), its Receptor (uPAR), and Inhibitor (PAI‐1) in Human Breast Carcinomas and Their Clinical Relevance

Serine proteases convert plasminogen to plasmin which is involved in tissue remodeling under physiologic and pathophysiologic conditions, including breast carcinoma invasion and progression. Both urokinase‐type plasminogen activator (uPA) and pro‐uPA associate with uPA receptor (uPAR) on target cell...

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Bibliographic Details
Published in:J Clin Lab Anal
Main Authors: Andres, Sarah A., Edwards, Angelena B., Wittliff, James L.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2012
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6807482/
https://ncbi.nlm.nih.gov/pubmed/22467324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.21488
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