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Programmed increases in LXRα induced by paternal alcohol use enhance offspring metabolic adaptation to high-fat diet induced obesity

OBJECTIVES: Paternally inherited alterations in epigenetic programming are emerging as relevant factors in numerous disease states, including the growth and metabolic defects observed in fetal alcohol spectrum disorders. In rodents, chronic paternal alcohol use induces fetal growth restriction, as w...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Chang, Richard C., Thomas, Kara N., Bedi, Yudhishtar S., Golding, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6807343/
https://ncbi.nlm.nih.gov/pubmed/31767168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.09.016
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