Depletion of Caveolin-1 in Type 2 Diabetes Model Induces Alzheimer's Disease Pathology Precursors

Type 2 diabetes mellitus (T2DM) is a risk factor for the development of late-onset Alzheimer's disease (AD). However, the mechanism underlying the development of late-onset AD is largely unknown. Here we show that levels of the endothelial-enriched protein caveolin-1 (Cav-1) are reduced in the...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Bonds, Jacqueline A., Shetti, Aashutosh, Bheri, Abdullah, Chen, Zhenlong, Disouky, Ahmed, Tai, Leon, Mao, Mao, Head, Brian P., Bonini, Marcelo G., Haus, Jacob M., Minshall, Richard D., Lazarov, Orly
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6807274/
https://ncbi.nlm.nih.gov/pubmed/31527120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0730-19.2019
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