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High‐performance Liquid Chromatographic Ultraviolet Detection of Nilotinib in Human Plasma from Patients with Chronic Myelogenous Leukemia, and Comparison with Liquid Chromatography‒Tandem Mass Spectrometry

BACKGROUND: A method for determining nilotinib concentration in human plasma is proposed using high‐performance liquid chromatography and ultraviolet detection. MATERIALS & METHODS: Nilotinib and the internal standard dasatinib were separated using a mobile phase of 0.5% Na(2)PO(4)H(2)O (pH 2.5)...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Nakahara, Ryosuke, Satho, Yuhki, Itoh, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6807079/
https://ncbi.nlm.nih.gov/pubmed/27194024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.21975
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