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Amino Acid Prevalence of HIV-1 pol Mutations by Direct Polymerase Chain Reaction and Single Genome Sequencing

The presence of many highly unusual HIV-1 mutations at a minority variant threshold by next-generation sequence (NGS) may indicate that a high proportion of variants at or just above the threshold represent PCR errors. The validity of this hypothesis depends on the concept that highly unusual mutati...

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Publicat a:AIDS Res Hum Retroviruses
Autors principals: Tzou, Philip L., Rhee, Soo-Yon, Shafer, Robert W.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc., publishers 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6806363/
https://ncbi.nlm.nih.gov/pubmed/31317771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2018.0289
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