The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets

Big defensins, ancestors of β-defensins, are composed of a β-defensin-like C-terminal domain and a globular hydrophobic ancestral N-terminal domain. This unique structure is found in a limited number of phylogenetically distant species, including mollusks, ancestral chelicerates, and early-branching...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Loth, Karine, Vergnes, Agnès, Barreto, Cairé, Voisin, Sébastien N., Meudal, Hervé, Da Silva, Jennifer, Bressan, Albert, Belmadi, Nawal, Bachère, Evelyne, Aucagne, Vincent, Cazevielle, Chantal, Marchandin, Hélène, Rosa, Rafael Diego, Bulet, Philippe, Touqui, Lhousseine, Delmas, Agnès F., Destoumieux-Garzón, Delphine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805989/
https://ncbi.nlm.nih.gov/pubmed/31641083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01821-19
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