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Prokaryotic Genome Expansion Is Facilitated by Phages and Plasmids but Impaired by CRISPR

Viruses and plasmids can introduce novel DNA into bacterial cells, thereby creating an opportunity for genome expansion; conversely, CRISPR, the prokaryotic adaptive immune system, which targets and eliminates foreign DNAs, may impair genome expansions. Recent studies presented conflicting results o...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Gao, Na L., Chen, Jingchao, Wang, Teng, Lercher, Martin J., Chen, Wei-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805729/
https://ncbi.nlm.nih.gov/pubmed/31681190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02254
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