A novel BMI-1 inhibitor QW24 for the treatment of stem-like colorectal cancer

BACKGROUND: Cancer-initiating cell (CIC), a functionally homogeneous stem-like cell population, is resonsible for driving the tumor maintenance and metastasis, and is a source of chemotherapy and radiation-therapy resistance within tumors. Targeting CICs self-renewal has been proposed as a therapeut...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Wang, Jinhua, Xing, Yajing, Wang, Yingying, He, Yundong, Wang, Liting, Peng, Shihong, Yang, Lianfang, Xie, Jiuqing, Li, Xiaotao, Qiu, Wenwei, Yi, Zhengfang, Liu, Mingyao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805542/
https://ncbi.nlm.nih.gov/pubmed/31640758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1392-8
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