The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation

BACKGROUND: Cells have evolved quality control mechanisms to ensure protein homeostasis by detecting and degrading aberrant mRNAs and proteins. A common source of aberrant mRNAs is premature polyadenylation, which can result in non-functional protein products. Translating ribosomes that encounter po...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Genome Biol
Main Authors: Hildebrandt, Andrea, Brüggemann, Mirko, Rücklé, Cornelia, Boerner, Susan, Heidelberger, Jan B., Busch, Anke, Hänel, Heike, Voigt, Andrea, Möckel, Martin M., Ebersberger, Stefanie, Scholz, Anica, Dold, Annabelle, Schmid, Tobias, Ebersberger, Ingo, Roignant, Jean-Yves, Zarnack, Kathi, König, Julian, Beli, Petra
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805484/
https://ncbi.nlm.nih.gov/pubmed/31640799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1814-0
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares