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Mutation analysis and clinical characterization of Iranian patients with mucopolysaccharidosis type I

BACKGROUND: Mucopolysaccharidosis type I (MPSI) is a rare autosomal recessive disorder caused by a deficiency of α‐l‐iduronidase (IDUA) encoded by the IDUA gene. We examined the mutation spectrum of the IDUA gene to explain the clinical, biochemical, and molecular features in 21 Iranian patients wit...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Taghikhani, Mohammad, Khatami, Shohreh, Abdi, Mohammad, Hakhamaneshi, Mohammad Said, Alaei, Mohammad Reza, Zamanfar, Daniel, Vakili, Rahim
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805319/
https://ncbi.nlm.nih.gov/pubmed/31386236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.22963
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