Celecoxib With Neoadjuvant Chemotherapy for Breast Cancer Might Worsen Outcomes Differentially by COX-2 Expression and ER Status: Exploratory Analysis of the REMAGUS02 Trial

PURPOSE: The overexpression of cyclooxygenase 2 (COX-2) gene, also known as prostaglandin-endoperoxide synthase 2 (PTGS2), occurs in breast cancer, but whether it affects response to anticox drugs remains unclear. We investigated the relationships between PTGS2 expression, celecoxib use during neoad...

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Publicado en:J Clin Oncol
Autores principales: Hamy, Anne-Sophie, Tury, Sandrine, Wang, Xiaofei, Gao, Junheng, Pierga, Jean-Yves, Giacchetti, Sylvie, Brain, Etienne, Pistilli, Barbara, Marty, Michel, Espié, Marc, Benchimol, Gabriel, Laas, Enora, Laé, Marick, Asselain, Bernard, Aouchiche, Brice, Edelman, Martin, Reyal, Fabien
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Clinical Oncology 2019
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ORIGINAL REPORTS
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804843/
https://ncbi.nlm.nih.gov/pubmed/30702971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.18.00636
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