Neurosteroids as novel antidepressants and anxiolytics: GABA-A receptors and beyond

The recent FDA approval of the neurosteroid, brexanolone (allopregnanolone), as a treatment for women with postpartum depression, and successful trials of a related neuroactive steroid, SGE-217, for men and women with major depressive disorder offer the hope of a new era in treating mood and anxiety...

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Publicado en:Neurobiol Stress
Autores principales: Zorumski, Charles F., Paul, Steven M., Covey, Douglas F., Mennerick, Steven
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2019
Materias:
Articles from the Special Issue on Allopregnanolone role in the neurobiology of stress and mood disorders; Edited by Graziano Pinna
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804800/
https://ncbi.nlm.nih.gov/pubmed/31649968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynstr.2019.100196
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