Parallel Comparison of 4-1BB or CD28 Co-stimulated CD19-Targeted CAR-T Cells for B Cell Non-Hodgkin’s Lymphoma

CD19-targeted chimeric antigen receptor-T (CAR-T) cells with CD28 or 4-1BB (28z CAR-T and BBz CAR-T) have shown great promise to treat relapsed or refractory (r/r) B cell non-Hodgkin’s lymphoma (B-NHL). However, comparison of their clinical outcomes has never been reported. This study investigated t...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Ying, Zhitao, He, Ting, Wang, Xiaopei, Zheng, Wen, Lin, Ningjing, Tu, Meifeng, Xie, Yan, Ping, Lingyan, Zhang, Chen, Liu, Weiping, Deng, Lijuan, Qi, Feifei, Ding, Yanping, Lu, Xin-an, Song, Yuqin, Zhu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804784/
https://ncbi.nlm.nih.gov/pubmed/31650026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2019.08.002
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