Induction Apoptosis of Erinacine A in Human Colorectal Cancer Cells Involving the Expression of TNFR, Fas, and Fas Ligand via the JNK/p300/p50 Signaling Pathway With Histone Acetylation

Erinacine A, which is one of the major bioactive diterpenoid compounds extracted from cultured mycelia of H. erinaceus, displays great antitumorigenic activity. However, the molecular mechanisms underlying erinacine A inducing cancer cell apoptosis in colorectal cancer (CRC) remain unclear. This stu...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Lee, Ko-Chao, Lee, Kam-Fai, Tung, Shui-Yi, Huang, Wen-Shih, Lee, Li-Ya, Chen, Wan-Ping, Chen, Chin-Chu, Teng, Chih-Chuan, Shen, Chien-Heng, Hsieh, Meng-Chiao, Kuo, Hsing-Chun
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804634/
https://ncbi.nlm.nih.gov/pubmed/31680958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01174
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