Inactivation of TFEB and NF-κB by marchantin M alleviates the chemotherapy-driven pro-tumorigenic senescent secretion

It is critical to regulate the senescence-associated secretory phenotype (SASP) due to its effect on promoting malignant phenotypes and limiting the efficiency of cancer therapy. In this study, we demonstrated that marchantin M (Mar-M, a naturally occurring bisbibenzyl) suppressed pro-inflammatory S...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Niu, Huanmin, Qian, Lilin, Sun, Bin, Liu, Wenjian, Wang, Fang, Wang, Qian, Ji, Xiaotian, Luo, Yanhai, Nesa, Effat Un, Lou, Hongxiang, Yuan, Huiqing
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804491/
https://ncbi.nlm.nih.gov/pubmed/31649843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2019.08.007
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