Prenatal Testosterone Excess Disrupts Placental Function in a Sheep Model of Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is a common condition of reproductive-aged women. In a well-validated sheep model of PCOS, testosterone (T) treatment of pregnant ewes culminated in placental insufficiency and intrauterine growth restriction of offspring. The purpose of this study was to explore spe...

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Опубликовано в: :Endocrinology
Главные авторы: Kelley, Angela S, Puttabyatappa, Muraly, Ciarelli, Joseph N, Zeng, Lixia, Smith, Yolanda R, Lieberman, Richard, Pennathur, Subramaniam, Padmanabhan, Vasantha
Формат: Artigo
Язык:Inglês
Опубликовано: Endocrine Society 2019
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804485/
https://ncbi.nlm.nih.gov/pubmed/31436841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2019-00386
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