Design and Synthesis of Novel 1,3-Thiazole and 2-Hydrazinyl-1,3-Thiazole Derivatives as Anti-Candida Agents: In Vitro Antifungal Screening, Molecular Docking Study, and Spectroscopic Investigation of their Binding Interaction with Bovine Serum Albumin

In the context of there being a limited number of clinically approved drugs for the treatment of Candida sp.-based infections, along with the rapid development of resistance to the existing antifungals, two novel series of 4-phenyl-1,3-thiazole and 2-hydrazinyl-4-phenyl-1,3-thiazole derivatives were...

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Publicado no:Molecules
Main Authors: Pricopie, Andreea-Iulia, Ionuț, Ioana, Marc, Gabriel, Arseniu, Anca-Maria, Vlase, Laurian, Grozav, Adriana, Găină, Luiza Ioana, Vodnar, Dan C., Pîrnău, Adrian, Tiperciuc, Brîndușa, Oniga, Ovidiu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804233/
https://ncbi.nlm.nih.gov/pubmed/31546673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24193435
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