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DNA repair in cancer initiation, progression, and therapy—a double-edged sword
Genomic and mitochondrial DNA molecules are exposed continuously for a damaging activity of chemical, physical, and internal genotoxicants. When DNA repair machinery is not working efficiently, the generation of DNA lesions and mutations leads to carcinogenic transformation. The high number of mutat...
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| Publicado no: | J Appl Genet |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6803590/ https://ncbi.nlm.nih.gov/pubmed/31468363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13353-019-00516-9 |
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