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Heterogeneity and Plasticity of Human Breast Cancer Cells in Response to Molecularly-Targeted Drugs

Non-responsive subpopulation of tumor cells, and acquired resistance in initially responsive cells are major challenges for cancer therapy with molecularly-targeted drugs. While point mutations are considered the major contributing factor to acquired resistance, in this study we explored the role of...

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Dades bibliogràfiques
Publicat a:Front Oncol
Autors principals: Bousoik, Emira, Nabiee, Ramina, Amirrad, Farideh, Nichols, Ashley, Witt, Rebecca, Mahdipoor, Parvin, Montazeri Aliabadi, Hamidreza
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803545/
https://ncbi.nlm.nih.gov/pubmed/31681603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01070
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