The Controversial Role of PD-1 and Its Ligands in Gynecological Malignancies

The programmed death-1 (PD-1, CD279) receptor with its ligands, programmed death ligand 1 (PD-L1, CD274, B7-H1), and programmed death ligand 2 (PD-L2, CD273, B7-DC), are the key players of one of the immune checkpoint pathways inhibiting T-cell activation. PD-L1 and PD-L2 are expressed in different...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Marinelli, Oliviero, Annibali, Daniela, Aguzzi, Cristina, Tuyaerts, Sandra, Amant, Frédéric, Morelli, Maria Beatrice, Santoni, Giorgio, Amantini, Consuelo, Maggi, Federica, Nabissi, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803534/
https://ncbi.nlm.nih.gov/pubmed/31681606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01073
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