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Pediatric Acute Myeloid Leukemia (AML): From Genes to Models Toward Targeted Therapeutic Intervention

This review aims to provide an overview of the current knowledge of the genetic lesions driving pediatric acute myeloid leukemia (AML), emerging biological concepts, and strategies for therapeutic intervention. Hereby, we focus on lesions that preferentially or exclusively occur in pediatric patient...

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Detalhes bibliográficos
Publicado no:Front Pediatr
Main Authors: Mercher, Thomas, Schwaller, Juerg
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803505/
https://ncbi.nlm.nih.gov/pubmed/31681706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2019.00401
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