Heterologous Production and Functional Characterization of Ageritin, a Novel Type of Ribotoxin Highly Expressed during Fruiting of the Edible Mushroom Agrocybe aegerita

Fungi produce various defense proteins against antagonists, including ribotoxins. These toxins cleave a single phosphodiester bond within the universally conserved sarcin-ricin loop of ribosomes and inhibit protein biosynthesis. Here, we report on the structure and function of ageritin, a previously...

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Vydáno v:Appl Environ Microbiol
Hlavní autoři: Tayyrov, Annageldi, Azevedo, Sophie, Herzog, Robert, Vogt, Eva, Arzt, Simon, Lüthy, Peter, Müller, Pie, Rühl, Martin, Hennicke, Florian, Künzler, Markus
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
Genetics and Molecular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803303/
https://ncbi.nlm.nih.gov/pubmed/31444206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01549-19
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