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Herpes Simplex Virus 1 MicroRNA miR-H28 Exported to Uninfected Cells in Exosomes Restricts Cell-to-Cell Virus Spread by Inducing Gamma Interferon mRNA

An earlier report showed that herpes simplex virus 1 (HSV-1) expresses two microRNAs (miRNAs), miR-H28 and miR-H29, late in the infectious cycle. The miRNAs are packed in exosomes and, in recipient cells, restrict the transmission of virus from infected cells to uninfected cells. We now report that...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Huang, Rongquan, Wu, Jiaming, Zhou, Xusha, Jiang, Haifang, Guoying Zhou, Grace, Roizman, Bernard
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803268/
https://ncbi.nlm.nih.gov/pubmed/31413129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01005-19
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