Porcine RING Finger Protein 114 Inhibits Classical Swine Fever Virus Replication via K27-Linked Polyubiquitination of Viral NS4B

In the host, many RING domain E3 ligases have been reported to inhibit viral replication through various mechanisms. In a previous screen, we found that porcine RING finger protein 114 (pRNF114), a RING domain E3 ubiquitin ligase, inhibits classical swine fever virus (CSFV) replication. This study a...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zhang, Yuexiu, Zhang, Huawei, Zheng, Guang-Lai, Yang, Qian, Yu, Shaoxiong, Wang, Jinghan, Li, Su, Li, Lian-Feng, Qiu, Hua-Ji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803260/
https://ncbi.nlm.nih.gov/pubmed/31413123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01248-19
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