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The ICP0 Protein of Herpes Simplex Virus 1 (HSV-1) Downregulates Major Autophagy Adaptor Proteins Sequestosome 1 and Optineurin during the Early Stages of HSV-1 Infection

Herpes simplex virus 1 (HSV-1) infects mucosal epithelial cells and establishes lifelong infections in sensory neurons. Following reactivation, the virus is transferred anterograde to the initial site of infection or to sites innervated by infected neurons, causing vesicular lesions. Upon immunosupp...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Waisner, Hope, Kalamvoki, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803258/
https://ncbi.nlm.nih.gov/pubmed/31375597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01258-19
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