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Methylation determines the extracellular calcium sensitivity of the leak channel NALCN in hippocampal dentate granule cells
The sodium leak channel NALCN is a key player in establishing the resting membrane potential (RMP) in neurons and transduces changes in extracellular Ca(2+) concentration ([Ca(2+)](e)) into increased neuronal excitability as the downstream effector of calcium-sensing receptor (CaSR). Gain-of-functio...
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| Publicado no: | Exp Mol Med |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6802672/ https://ncbi.nlm.nih.gov/pubmed/31601786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0325-0 |
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