Particulate matter-induced senescence of skin keratinocytes involves oxidative stress-dependent epigenetic modifications

Ambient air particulate matter (PM) induces senescence in human skin cells. However, the underlying mechanisms remain largely unknown. We investigated how epigenetic regulatory mechanisms participate in cellular senescence induced by PM with a diameter <2.5 (PM(2.5)) in human keratinocytes and mo...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Ryu, Yea Seong, Kang, Kyoung Ah, Piao, Mei Jing, Ahn, Mee Jung, Yi, Joo Mi, Bossis, Guillaume, Hyun, Young-Min, Park, Chang Ook, Hyun, Jin Won
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802667/
https://ncbi.nlm.nih.gov/pubmed/31551408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0305-4
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