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The flagellin-TLR5-Nox4 axis promotes the migration of smooth muscle cells in atherosclerosis
We hypothesized that NADPH oxidase 4 (Nox4) is involved in the formation of neointimal atherosclerotic plaques through the migration of smooth muscle cells (SMCs) in response to flagellin. Here, we demonstrate that TLR5-mediated Nox4 activation regulates the migration of SMCs, leading to neointimal...
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| Publicat a: | Exp Mol Med |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6802658/ https://ncbi.nlm.nih.gov/pubmed/31292433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0275-6 |
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