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Adaptor protein CrkII negatively regulates osteoblast differentiation and function through JNK phosphorylation

The adaptor protein CrkII is involved in several biological activities, including mitogenesis, phagocytosis, and cytoskeleton reorganization. Previously, we demonstrated that CrkII plays an important role in osteoclast differentiation and function through Rac1 activation both in vitro and in vivo. I...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Kim, Jung Ha, Kim, Kabsun, Kim, Inyoung, Seong, Semun, Nam, Kwang-Il, Kim, Kyung Keun, Kim, Nacksung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802640/
https://ncbi.nlm.nih.gov/pubmed/31554784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0314-3
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