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Altered activity in the nucleus raphe magnus underlies cortical hyperexcitability and facilitates trigeminal nociception in a rat model of medication overuse headache

BACKGROUND: The pathogenesis of medication overuse headache (MOH) involves hyperexcitability of cortical and trigeminal neurons. Derangement of the brainstem modulating system, especially raphe nuclei may contribute to this hyperexcitability. The present study aimed to investigate the involvement of...

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Detalhes bibliográficos
Publicado no:BMC Neurosci
Main Authors: Potewiratnanond, Prangtip, le Grand, Supang Maneesri, Srikiatkhachorn, Anan, Supronsinchai, Weera
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802338/
https://ncbi.nlm.nih.gov/pubmed/31638891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-019-0536-2
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