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Cacna1b alternative splicing impacts excitatory neurotransmission and is linked to behavioral responses to aversive stimuli

Presynaptic Ca(V)2.2 channels control calcium entry that triggers neurotransmitter release at both central and peripheral synapses. The Cacna1b gene encodes the α1-pore forming subunit of Ca(V)2.2 channels. Distinct subsets of splice variants of Ca(V)2.2 derived from cell-specific alternative splici...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Bunda, Alexandra, LaCarubba, Brianna, Bertolino, Melanie, Akiki, Marie, Bath, Kevin, Lopez-Soto, Javier, Lipscombe, Diane, Andrade, Arturo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802325/
https://ncbi.nlm.nih.gov/pubmed/31630675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-019-0500-1
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