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Protective Effect of Phosphatidylserine Blockade in Sepsis Induced Organ Dysfunction

BACKGROUND: Phosphatidylserine (PS) is usually an intracellularly oriented cell membrane phospholipid. Externalized PS on activated cells is a signal for phagocytosis. In sepsis, persistent PS exposure is also a signal for activation of the coagulation and inflammatory cascades. As such, PS may be a...

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Detalhes bibliográficos
Publicado no:Surgery
Main Authors: Beattie, Genna, Cohan, Caitlin, Miraflor, Emily, Brigode, William, Victorino, Gregory P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802284/
https://ncbi.nlm.nih.gov/pubmed/31285044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2019.05.020
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