B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage

B-1a cells are long-lived, self-renewing innate-like B cells that predominantly inhabit the peritoneal and pleural cavities. In contrast to conventional B-2 cells, B-1a cells have a receptor repertoire that is biased towards bacterial and self-antigens, promoting a rapid response to infection and cl...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wong, Jason B., Hewitt, Susannah L., Heltemes-Harris, Lynn M., Mandal, Malay, Johnson, Kristen, Rajewsky, Klaus, Koralov, Sergei B., Clark, Marcus R., Farrar, Michael A., Skok, Jane A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802180/
https://ncbi.nlm.nih.gov/pubmed/31628339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12824-z
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