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Identification of New DR5 Agonistic Nanobodies and Generation of Multivalent Nanobody Constructs for Cancer Treatment

Current cancer therapeutics suffer from a lack of specificity in targeting tumor cells and cause severe side effects. Therefore, the design of highly specialized drugs comprising antibody derivatives inducing apoptosis in targeted cancer cells is considered to be a promising strategy. Drugs acting o...

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書目詳細資料
發表在:Int J Mol Sci
Main Authors: Sadeghnezhad, Golnaz, Romão, Ema, Bernedo-Navarro, Robert, Massa, Sam, Khajeh, Khosro, Muyldermans, Serge, Hassania, Sadegh
格式: Artigo
語言:Inglês
出版: MDPI 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801735/
https://ncbi.nlm.nih.gov/pubmed/31569768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20194818
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