Prognostic Factors and Biomarkers of Responses to Immune Checkpoint Inhibitors in Lung Cancer

Manipulation of the immune response is a game changer in lung cancer treatment, revolutionizing management. PD1 and CTLA4 are dynamically expressed on different T cell subsets that can either disrupt or sustain tumor growth. Monoclonal antibodies (MoAbs) against PD1/PDL1 and CTLA4 have shown that in...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bianco, Andrea, Perrotta, Fabio, Barra, Giusi, Malapelle, Umberto, Rocco, Danilo, De Palma, Raffaele
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801651/
https://ncbi.nlm.nih.gov/pubmed/31590386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20194931
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