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CDDO-Me Attenuates Vasogenic Edema and Astroglial Death by Regulating NF-κB p65 Phosphorylations and Nrf2 Expression Following Status Epilepticus

2-Cyano-3,12-dioxo-oleana-1,9(11)-dien-28-oic acid methyl ester (CDDO-Me) is a triterpenoid analogue of oleanolic acid that has anti-inflammatory, antioxidant, and neuroprotective activities. In the present study, we evaluate the effects of CDDO-Me on serum extravasation and astroglial death in the...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kim, Min-Ju, Park, Hana, Choi, Seo-Hyeon, Kong, Min-Jeong, Kim, Ji-Eun, Kang, Tae-Cheon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801369/
https://ncbi.nlm.nih.gov/pubmed/31574956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20194862
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