Eluted 25-hydroxyvitamin D(3) from Radially aligned Nanofiber Scaffolds Enhances Cathelicidin Production While Reducing Inflammatory Response in Human Immune System-Engrafted Mice

Vitamin D(3) modulates immune response, induces endogenous antimicrobial peptide production, and enhances innate immunity to defend against infections. These findings suggest that incorporating vitamin D(3) into medical devices or scaffolds could positively modulate host immune response and prevent...

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Pubblicato in:Acta Biomater
Autori principali: Chen, Shixuan, Ge, Liangpeng, Wang, Hongjun, Cheng, Yan, Gorantla, Santhi, Poluektova, Larisa Y., Gombart, Adrian F., Xie, Jingwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801031/
https://ncbi.nlm.nih.gov/pubmed/31386930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2019.08.005
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