Using a genetic risk score to calculate the optimal age for an individual to undergo coronary artery calcium screening

BACKGROUND: Genetic risk scores (GRSs) have been associated with CHD events and coronary artery calcium (CAC). We sought to evaluate the ability of a GRS to improve CAC as a screening test. METHODS: Using the results of the most recent genome-wide association studies, we calculated a GRS in 6660 ind...

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Pubblicato in:J Cardiovasc Comput Tomogr
Autori principali: Severance, Lauren M, Contijoch, Francisco J, Carter, Hannah, Fan, Chun C, Seibert, Tyler M, Dale, Anders M, McVeigh, Elliot R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801022/
https://ncbi.nlm.nih.gov/pubmed/31104941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcct.2019.05.005
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